Regulation of MntH by a dual Mn(II)- and Fe(II)-dependent transcriptional repressor (DR2539) in Deinococcus radiodurans.
The high intracellular Mn/Fe ratio click here observed within the bacteria Deinococcus radiodurans may contribute to its remarkable resistance to environmental stresses.We isolated DR2539, a novel regulator of intracellular Mn/Fe homeostasis in D.radiodurans.Electrophoretic gel mobility shift assays (EMSAs) revealed that DR2539 binds specifically t